The biggest box office failures of all time are typically measured by the extent of their financial losses rather than just their underperformance at the box office. Some of the most notable ones include: " Mars Needs Moms " (2011) - This animated film from Disney is often cited as one of the biggest box office failures. It had an estimated production budget of around $150 million but only grossed approximately $39 million worldwide. The film's poor performance was attributed to a combination of factors, including unappealing marketing, a lackluster story, and the uncanny valley effect caused by the motion capture animation. " John Carter " (2012) - Based on the classic sci-fi novels by Edgar Rice Burroughs, "John Carter" had an estimated production budget of around $250 million. However, it struggled to find an audience and only grossed around $284 million worldwide. Despite having a loyal fan base, the film's marketing campaign failed to effectiv